Zeb1 mediates EMT/plasticity-associated ferroptosis sensitivity in cancer cells by regulating lipogenic enzyme expression and phospholipid composition. Schwab, A, Rao, Z, Zhang, J, Gollowitzer, A, Siebenkäs, K, Bindel, N, D'Avanzo, E, van Roey, R, Hajjaj, Y, Özel, E, Armstark, I, Bereuter, L, Su, F, Grander, J, Bonyadi Rad, E, Groenewoud, A, Engel, FB, Bell, GW, Henry, WS, Angeli, JPF, Stemmler, MP, Brabletz, S, Koeberle, A, Brabletz, T. 2024. Nat Cell Biol. Epub ahead of print.
doi: 10.1038/s41556-024-01464-1
PMID: 39009641

ATF3 characterizes aggressive drug-tolerant persister cells in HGSOC. Böpple, K, Oren, Y, Henry, WS, Dong, M, Weller, S, Thiel, J, Kleih, M, Gaißler, A, Zipperer, D, Kopp, HG et al.. 2024. Cell Death Dis 15, 290.
doi: 10.1038/s41419-024-06674-x
PMID:38658567

Ether lipids influence cancer cell fate by modulating iron uptake. Henry, WS, Müller, S, Yang, JS, Innes-Gold, S, Das, S, Reinhardt, F, Sigmund, K, Phadnis, VV, Wan, Z, Eaton, E et al.. 2024. bioRxiv.
doi: 10.1101/2024.03.20.585922
PMID:38562716

MMD collaborates with ACSL4 and MBOAT7 to promote polyunsaturated phosphatidylinositol remodeling and susceptibility to ferroptosis. Phadnis, VV, Snider, J, Varadharajan, V, Ramachandiran, I, Deik, AA, Lai, ZW, Kunchok, T, Eaton, EN, Sebastiany, C, Lyakisheva, A, Vaccaro KD, Allen J, Yao Z, Wong V, Geng B, Weiskopf K, Clish CB, Brown JM, Stagljar I, Weinberg RA, Henry WS. 2023. Cell Rep 42, 113023.
doi: 10.1016/j.celrep.2023.113023
PMID:37691145

Plasticity of ether lipids promotes ferroptosis susceptibility and evasion. Zou, Y*, Henry, WS*, Ricq, EL*, Graham, ET, Phadnis, VV, Maretich, P, Paradkar, S, Boehnke, N, Deik, AA, Reinhardt, F et al.. 2020. Nature 585, 603-608.
doi: 10.1038/s41586-020-2732-8
PMID:32939090

Pentraxin-3 is a PI3K signaling target that promotes stem cell-like traits in basal-like breast cancers. Thomas, C, Henry, W, Cuiffo, BG, Collmann, AY, Marangoni, E, Benhamo, V, Bhasin, MK, Fan, C, Fuhrmann, L, Baldwin, AS et al.. 2017. Sci Signal 10.
doi: 10.1126/scisignal.aah4674
PMID:28223411

LINC00520 is induced by Src, STAT3, and PI3K and plays a functional role in breast cancer. Henry, WS, Hendrickson, DG, Beca, F, Glass, B, Lindahl-Allen, M, He, L, Ji, Z, Struhl, K, Beck, AH, Rinn, JL et al.. 2016. Oncotarget 7, 81981-81994.
doi: 10.18632/oncotarget.11962
PMID:27626181